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60 seconds are all it takes to protect your health and that of your patients

Did you know that pre-procedural mouthrinsing with Chlorhexidine + Cetylpyridinium Chloride (CHX+CPC) can protect patients and professionals in the dental clinic from bacterial and viral infection and cross-contamination? 

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The PER-IADR congress in Marseille (15-17 September 2022) showed the importance of using pre-procedural mouthrinsing to help protect against infection in the dental practice.

If you could not attend, watch this short video with the highlights of the congress.

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The entire composition of a mouthwash has a significant influence on its efficacy. The presence of an active component in a formulation, such as CHX, does not ensure that the product is effective.

What are the active components of an ideal formulation?


CHXChlorhexidine (CHX) is considered the gold standard antiseptic. It is the antiseptic with the highest antibacterial, anti-plaque and anti-gingivitis activity. It has a substantivity of 12 hours and a broad spectrum of action against bacteria, viruses and fungi.

CPCCetylpyridinium Chloride (CPC) is a safe and effective daily-use antiseptic with antiplaque action and a substantivity of between 3 and 5 hours. It also has a broad spectrum of action against different types of bacteria, fungi and some viruses.

Products with CHX + CPC 

What has dentistry learned from the pandemic?

Watch the main conclusions of the experts during the PER-IADR (September 15-17, 2022).

David Herra▶ Oral and systemic health - is there a "new" link with COVID-19?

 

Professor David Herrera
 

Full Professor of Periodontology Computense University of Madrid (UCM) Madrid, Spain.

Fridus van der Weijden Aerosol in the dental setting: a misty topic

Professor Fridus van der Weijden


Clinic fo Periodontology and Implantology Utrecht and the Academic Centre for Dentistry Amsterdam (ACTA).

 

Dieter Hoffmann The role of the oral cavity in SARS-CoV-2 and other viral infections
Dr. Dieter Hoffmann

 
Manager of the Clinical Virology laboratory, Institute of Virology, TU Munich, Germany.

 

Fabian Cieplik Preprocedural mouthwashes for infection control
 

PD Dr. Fabian Cieplik


 Department of Conservative Dentistry and Periodontology, University Hospital Regensburg. Germany.

Scientific evidence of CPC against SARS-CoV-2 (IN VIVO studies)

  • Rinsing and gargling for 60 seconds with a commercially available mouthwash (CHX + CPC, 0.05% each) significantly reduced viral infectivity in SARS-CoV-2 positive patients as assessed by virus culture. Bonn et al. (2022).
  • Oral rinsing for 60 seconds with mouthwashes containing 0.07% Cetylpyridinium Chloride (CPC). Alemany et. al (2022).
    reduces the amount of infectious viruses in saliva 
    could help prevent the transmission of SARS-CoV-2

  • Rinsing with 0.07% CPC mouthwash produced a statistically significant reduction in the infectivity of the saliva of COVID-19-positive patients. Tarragó et al. (2021).

  • The use of CPC mouthwash produced the greatest reductions in SARS-CoV-2 salivary viral load, and this effect lasted for at least 1 hour after rinsing. Eduardo et al. (2021).

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References:
A.  Alemany,  D.  Perez-Zsolt,  D.  Raïch-Regué,  J.  Muñoz-Basagoiti,  D.  Ouchi,  C.  Laporte-Villar,    B.    Baro,    N.    Henríquez,    N.Prat,    M.    Ochoa    Gianetto,    M.    Garcia  Sánchez-Paniagua,  N.Larrosa  Henríquez,  J.  Moreno  Vicente,  J.  Ara,  M.A. Rodriguez-Arias, J. Puig, I. Blanco, C. Casañ Lopez, Á. Hernández, A.E. Bordoy, C. Esteban Redondo, V. González Soler, M. Giménez, V.Blanc, R. León, J. Gispert, B. Clotet, N. Izquierdo- Useros, O. Mitjà. Cetylpyridinium Chloride Mouthwash to Reduce  Shedding  of    Infectious    SARS-CoV-2:    A    Double-Blind    Randomized  Clinical  Trial.  Journal  of  Dental  Research.  First  Published  June  21,  2022  Research  Article. https://doi.org/10.1177/00220345221102310
Muñoz-Basagoiti J, Perez-Zsolt D, León R, Blanc V, Raïch-Regué D, Cano-Sarabia M, Trinité B, Pradenas E, Blanco J, Gispert J, et al. 2021. Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro. J Dent Res. 100(11):1265–1272.
Herrera D, Serrano J, Roldán S, Sanz M. Is the oral cavity relevant in SARS-CoV-2 pandemic? [published online ahead of print, 2020 Jun 23]._Clin Oral Investig. 2020;1-6.
Eduardo FP, Corrêa L, Heller D, Daep CA, Benitez C, Malheiros Z, Stewart B, Ryan M, Machado CM, Hamerschlak N, Rebello Pinho JR, Bezinelli LM. Salivary SARS-CoV-2 load reduction with mouthwash use: A randomized pilot clinical trial. Heliyon. 2021 Jun;7(6):e07346.
Tarrago  R  ,Aza  M,  Lallana  MJ,  Serrano  D,  Millán  Y,  Refusta  R, Fuentes  R,  Bueno  J,  Algarate  S,  Millán  E.  Ensayo  clínico aleatorizado  para  valorar  el  impacto  de  la  intervención  oral  con Cloruro  de  Cetilpiridinio  para  disminuir  la  carga  viral  de  SARS-CoV-2. Poster presentado en el Congreso SEPA Sevilla 21 (noviembre 2021), ganador del primer premio en la categoría de higienistas.